The Vth WORKSHOP CHALLENGES OF NEW PHYSICS IN SPACE will have thematic review and advanced topic talks, delivered by invited Brazilian and overseas speakers. The subjects of the talks include testing the foundations of the standard cosmological model, Copernican principle, variation of fundamental constants, averaging, backreaction and fitting problems in cosmology, gamma-ray bursts (open issues, current view and status, use as cosmological tools and future developments), all-scale exploration of alternative theories of gravity. Besides, there will be works selected for panel presentation, and plenty of time for discussion among the participants.